2-Hexyldecanoic acid
Based on 1 Customer Validation
2-Hexyldecanoic acid is a lipid containing one carboxylic acid group and two non-polar tails. In the presence of EDC, HATU and DCC, carboxylic acid groups can undergo continuous amide coupling reactions with amine-containing biomolecules to form stable amide bonds. 2-Hexyldecanoic acid can be used as an aerolysin inhibitor to prevent bacterial pathogens. 2-Hexyldecanoic acid can cause contact dermatitis.
For research use only. We do not sell to patients.
- Purity: 99.71%
- CAS No.: 25354-97-6
- Formula: C16H32O2
- Molecular Weight:256.42
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2-Hexyldecanoic acid can interact with aerolysin, stably form complexes, and inhibit the aerolysin oligomerization of A. hydrophila[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 25354-97-6
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Appearance Liquid (Density: 0.88 g/cm3)
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Molecular Weight 256.42
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Formula C16H32O2
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Color Colorless to light yellow
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SMILES
CCCCCCCCC(CCCCCC)C(=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (389.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (9.75 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
References
[2]. Arumugam M, et al. Evaluating Biofilm Inhibitory Potential in Fish Pathogen, Aeromonas hydrophila by Agricultural Waste Extracts and Assessment of Aerolysin Inhibitors Using In Silico Approach. Antibiotics (Basel). 2023 May 11;12(5):891. [Content Brief]
[3]. Kimura M, et al. Contact dermatitis due to 2-hexyldecanoic acid (isopalmitate) in a lipstick. Contact Dermatitis. 1999 Aug;41(2):99-100. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8999 mL | 19.4993 mL | 38.9985 mL | 97.4963 mL |
| 5 mM | 0.7800 mL | 3.8999 mL | 7.7997 mL | 19.4993 mL | |
| 10 mM | 0.3900 mL | 1.9499 mL | 3.8999 mL | 9.7496 mL | |
| 15 mM | 0.2600 mL | 1.3000 mL | 2.5999 mL | 6.4998 mL | |
| 20 mM | 0.1950 mL | 0.9750 mL | 1.9499 mL | 4.8748 mL | |
| 25 mM | 0.1560 mL | 0.7800 mL | 1.5599 mL | 3.8999 mL | |
| 30 mM | 0.1300 mL | 0.6500 mL | 1.3000 mL | 3.2499 mL | |
| 40 mM | 0.0975 mL | 0.4875 mL | 0.9750 mL | 2.4374 mL | |
| 50 mM | 0.0780 mL | 0.3900 mL | 0.7800 mL | 1.9499 mL | |
| 60 mM | 0.0650 mL | 0.3250 mL | 0.6500 mL | 1.6249 mL | |
| 80 mM | 0.0487 mL | 0.2437 mL | 0.4875 mL | 1.2187 mL | |
| 100 mM | 0.0390 mL | 0.1950 mL | 0.3900 mL | 0.9750 mL |
2-Hexyldecanoic acid Related Classifications
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