2. Anti-infection
  3. Bacterial
  4. CBA-4

CBA-4 is an L,D-transpeptidase inhibitor. CBA-4 covalently acylates the active site of L,D-transpeptidase to form a stable acylenzyme adduct. CBA-4 can be used for research on bacterial resistance.

For research use only. We do not sell to patients.

CBA-4

CBA-4 Chemical Structure

CAS No. : 2114983-08-1

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CBA-4 Related Antibodies

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Description

CBA-4 is an L,D-transpeptidase inhibitor. CBA-4 covalently acylates the active site of L,D-transpeptidase to form a stable acylenzyme adduct. CBA-4 can be used for research on bacterial resistance[1].

In Vitro

CBA-4 (39 μM; 15 min) fully acylates purified Ldtfm and forms a stable acyl-enzyme adduct that shows no detectable hydrolysis after 3 h of incubation[1].
CBA-4 (30 min) undergoes copper-catalyzed azide–alkyne cycloaddition (CuAAC) with 3-azido-7-hydroxycoumarin at an initial rate of 0.56 μM min−1, reaching 21% conversion after 30 min of incubation at room temperature[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CBA-4 Related Antibodies
Molecular Weight

295.35

Formula

C14H17NO4S
CAS No.
SMILES

OC(C1=C(SCCC#C)[C@H](C)[C@@]([C@@]2([H])[C@H](O)C)([H])N1C2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CBA-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CBA-42114983-08-1CBA4CBA 4Bacterial3-azido-7-hydroxycoumarincopper-catalyzed cycloadditionCuAACLD-transpeptidaseazido-containing partnersInhibitorinhibitorinhibit

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