2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 298

Antibacterial agent 298 exhibits significant antibacterial activity against Pseudomonas putida (ATCC 25922) with an IC50 4.48 µg/mL. Antibacterial agent 298 shows strong antibiofilm activity. Antibacterial agent 298 also inhibits approximately 50% of biofilm formation in L. lactis and P. putida. Antibacterial agent 298 can be used for the study of Bacterial infections caused by multidrug-resistant bacteria (MDR).

For research use only. We do not sell to patients.

Antibacterial agent 298

Antibacterial agent 298 Chemical Structure

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Antibacterial agent 298 Related Antibodies

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Description

Antibacterial agent 298 exhibits significant antibacterial activity against Pseudomonas putida (ATCC 25922) with an IC50 4.48 µg/mL. Antibacterial agent 298 shows strong antibiofilm activity. Antibacterial agent 298 also inhibits approximately 50% of biofilm formation in L. lactis and P. putida. Antibacterial agent 298 can be used for the study of Bacterial infections caused by multidrug-resistant bacteria (MDR)[1].

In Vitro

Antibacterial agent 298 (Compound 3a) (10-100 μg/mL, 24 h) shows good antibacterial effects against both Gram-positive and Gram-negative bacteria, especially against Gram-negative bacteria[1].
Antibacterial agent 298 exhibits concentration-dependent anti-biofilm activity against all tested strains: Lactococcus lactis (MIC50 = 24.8 μg/mL); Bacillus megaterium (MIC50 = 48.6 μg/mL); Pseudomonas putida (MIC50 = 28.3 μg/mL); and Marcescens Serratia (MIC50 = 31.9 μg/mL)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 298 Related Antibodies

Cell Viability Assay[1]

Cell Line: Pseudomonas putida (ATCC25922), Bacillus megaterium (QMB1551), Lactococcus Lactis (NZ900), Marcescens Serratia (NCTC10211)
Concentration: 10 μg/mL, 20 μg/mL, 30 μg/mL, 40 μg/mL, 50 μg/mL, 60 μg/mL, 70 μg/mL, 80 μg/mL, 90 μg/mL, 100 μg/mL
Incubation Time: 24 h
Result: Lactococcus Lactis (NZ900) (IC50 = 9.48 μg/mL)
Bacillus Megaterium (QMB1551) (IC50 = 7.02 μg/mL)
Pseudomonas putida (ATCC25922) (IC50 = 4.48 μg/mL)
Marcescens Serratia (NCTC10211) (IC50 = 17.26 μg/mL)
Molecular Weight

742.94

Formula

C45H58O9
SMILES

[H][C@]12CC([H])[C@@]3([H])[C@]4([H])CC[C@H]([C@@H](CCC(OC5=CC=C(C=C5OC)/C=C/C(CC(/C=C/C6=CC=C(C(OC)=C6)O)=O)=O)=O)C)[C@](C)4[C@@H](O)C[C@@]([H])3[C@@]1(C)CC[C@@H](O)C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antibacterial agent 298 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

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