Antibacterial agent 332
Antibacterial agent 332 is an inhibitor of DsbA from Escherichia coli (EcDsbA). Antibacterial agent 332 reduces the swarming motility of Escherichia coli without affecting bacterial growth. Antibacterial agent 332 can be used in the research of bacterial infections caused by Escherichia coli.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3106820-05-4
- 分子式: C26H23F2N3O6
- 分子量:511.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Antibacterial agent 332 (compound 17) (0-100 mM) binds to histidine-tagged E. coli DsbA, with a kinetic SPR KD of 2.2 μM and an equilibrium SPR KD of 2.8 μM[1].
Antibacterial agent 332 (50 μM; 180 s injection intervals) binds to Escherichia coli DsbA, with an ITC KD value of 1.5 μM determined based on the single-site binding model[1].
Antibacterial agent 332 inhibits Escherichia coli DsbA-mediated oxidation of native peptide substrates with an IC50 of 30 μM in peptide oxidation assays[1].
Antibacterial agent 332 (1 h, room temperature) shows a high enrichment rate in ASMS screening, indicating that it can form a stable complex with E. coli DsbA[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3106820-05-4
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分子量 511.47
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分子式 C26H23F2N3O6
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SMILES
FC1=CC(C[C@@H](CO)NC(C#CC2=CC(NC(C3=NOC(C)=C3)=O)=CC=C2)=O)=CC(F)=C1CC(OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antibacterial agent 332 関連分類
HY-182049 関連分類
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