Antibacterial agent 295
Antibacterial agent 295 is nitrofuran derivative. Antibacterial agent 295 is an antibiotic with anti-bacterial effects to S. aureus and E.coli. Antibacterial agent 295 showes an MIC of 0.78 μM in S. aureus USA300 and 1.6 μM in E.coli K12. Antibacterial agent 295 can be used for the research of infection .
For research use only. We do not sell to patients.
- Formula: C13H11N3O4
- Molecular Weight:273.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Description
In Vitro
Antibacterial agent 295 (Compound D8) shows anti-bacterial effects to SA USA300 and EC K12with MIC values of 0.78 and 1.56 μM[1].
Antibacterial agent 295 (16 μM, 0-6 h) shows bacteriostatic effects to E.coli[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 273.24
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Formula C13H11N3O4
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SMILES
NC1=CC=C(NC(/C=C/C2=CC=C([N+]([O-])=O)O2)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)