Penicillin G benzathine
Based on 1 Customer Validation
Penicillin G benzathine (Benzathine benzylpenicillin) is an antibiotic against many bacterial infections.
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 1538-09-6
- Formula: C48H56N6O8S2
- Molecular Weight:909.12
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Antibiotic Isoforms
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Biological Activity
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β-lactam |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1538-09-6
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Appearance Solid
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Molecular Weight 909.12
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Formula C48H56N6O8S2
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Color White to light yellow
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SMILES
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(CC3=CC=CC=C3)=O)N1C2=O)O.O=C([C@@H](C(C)(C)S[C@]4([H])[C@@H]5NC(CC6=CC=CC=C6)=O)N4C5=O)O.C7(CNCCNCC8=CC=CC=C8)=CC=CC=C7
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Synonyms
Benzathine benzylpenicillin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 175 mg/mL (192.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Bowen AC, et al. Short-course oral co-trimoxazole versus intramuscular benzathine benzylpenicillin for impetigo in a highly endemic region: an open-label, randomised, controlled, non-inferiority trial. Lancet. 2014 Dec 13;384(9960):2132-40. [Content Brief]
[2]. J A Yurchenco, et al. Substituted Penicillin Amides. Duration of Antibacterial Activity (Depot Effect) in Experimental Infections in Mice. Chemotherapy . 1972;17(6):405-15. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1000 mL | 5.4998 mL | 10.9996 mL | 27.4991 mL |
| 5 mM | 0.2200 mL | 1.1000 mL | 2.1999 mL | 5.4998 mL | |
| 10 mM | 0.1100 mL | 0.5500 mL | 1.1000 mL | 2.7499 mL | |
| 15 mM | 0.0733 mL | 0.3667 mL | 0.7333 mL | 1.8333 mL | |
| 20 mM | 0.0550 mL | 0.2750 mL | 0.5500 mL | 1.3750 mL | |
| 25 mM | 0.0440 mL | 0.2200 mL | 0.4400 mL | 1.1000 mL | |
| 30 mM | 0.0367 mL | 0.1833 mL | 0.3667 mL | 0.9166 mL | |
| 40 mM | 0.0275 mL | 0.1375 mL | 0.2750 mL | 0.6875 mL | |
| 50 mM | 0.0220 mL | 0.1100 mL | 0.2200 mL | 0.5500 mL | |
| 60 mM | 0.0183 mL | 0.0917 mL | 0.1833 mL | 0.4583 mL | |
| 80 mM | 0.0137 mL | 0.0687 mL | 0.1375 mL | 0.3437 mL | |
| 100 mM | 0.0110 mL | 0.0550 mL | 0.1100 mL | 0.2750 mL |