CJ-21,058
CJ-21,058 is a potent SecA inhibitor with an IC50 value of 15 µg/mL. CJ-21,058 inhibits ATP-dependent translocation of precursor proteins across a bacterial cell membrane. CJ-21,058 shows antibacterial activity against Gram-positive bacteria.
For research use only. We do not sell to patients.
- CAS No.: 405072-57-3
- Formula: C23H33NO4
- Molecular Weight:387.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 15 µg/mL (SecA)[1]
CJ-21,058 (0-20 µg/mL) shows antibacterial activity with MIC values of 5, >20, 5, >20 µg/mL for Staphylococcus aureus 01A1105, Streptococcus pyogenes 02C1068, Enterococcus faecalis 03A1069, Escherichia coli 51A0266, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 405072-57-3
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Molecular Weight 387.51
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Formula C23H33NO4
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SMILES
O/C([C@@]([C@@](CC[C@H]1C)([H])[C@](C1)([H])C=C2C)([C@@H]2/C=C/C)C)=C(C(N3C)=O)\C([C@@H]3CO)=O
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Structure Classification
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Initial Source
fungus CL47745
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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