405072-57-3
Chemical Structure
CJ-21,058
- CAS No.: 405072-57-3
- Formula:C23H33NO4
- Molecular Weight:387.51
IUPAC Name: (S,E)-3-(hydroxy((1S,2R,4aS,6R,8aR)-1,3,6-trimethyl-2-((E)-prop-1-en-1-yl)-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)methylene)-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione
InChIKey: ZTPMRDYXXHRMRU-VGYCBOMMSA-N
SMILES: O/C([C@@]([C@@](CC[C@H]1C)([H])[C@](C1)([H])C=C2C)([C@@H]2/C=C/C)C)=C(C(N3C)=O)\C([C@@H]3CO)=O
Biological Activity: CJ-21,058 is a potent SecA inhibitor with an IC50 value of 15 µg/mL. CJ-21,058 inhibits ATP-dependent translocation of precursor proteins across a bacterial cell membrane. CJ-21,058 shows antibacterial activity against Gram-positive bacteria[1].
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CJ-21,058 | CJ-21,058 is a potent SecA inhibitor with an IC50 value of 15 µg/mL. CJ-21,058 inhibits ATP-dependent translocation of precursor proteins across a bacterial cell membrane. CJ-21,058 shows antibacterial activity against Gram-positive bacteria. | |||||||||||||||||||||
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Keywords
