Erythromycin Ethylsuccinate (Synonyms: Erythromycin ethyl succinate; EES)

Cat. No.: HY-B0957 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Erythromycin Ethylsuccinate is an antibiotic useful for the treatment of a number of bacterial infections, has an antimicrobial spectrum similar to or slightly wider than that of penicillin. Erythromycin Ethylsuccinate has antiviral activity against HIV-1.

For research use only. We do not sell to patients.

Erythromycin Ethylsuccinate Chemical Structure

CAS No. : 1264-62-6

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Free Sample (0.1 - 0.5 mg)		Apply Now
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 66	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 66	In-stock	Estimated Time of Arrival: December 31
Solid
200 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Other Forms of Erythromycin Ethylsuccinate:

Erythromycin In-stock
Erythromycin ethylsuccinate-¹³C,d₃ Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

HIV-1

Clinical Trial

Molecular Weight

862.05

Appearance

Solid

Formula

C₄₃H₇₅NO₁₆

CAS No.

1264-62-6

SMILES

O=C(CCC(OCC)=O)O[C@H]([C@H]1N(C)C)[C@](O[C@H](C)C1)([H])O[C@@H]([C@](O)(C[C@H](C([C@@H]([C@@H](O)[C@@]2(O)C)C)=O)C)C)[C@H]([C@@H]([C@H](C(O[C@@H]2CC)=O)C)O[C@@](O[C@@H](C)[C@@H]3O)([H])C[C@@]3(C)OC)C

Structure Classification

Initial Source

Saccharopolyspora erythraea

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL (58.00 mM)

Ethanol : ≥ 33.33 mg/mL (38.66 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1600 mL	5.8001 mL	11.6003 mL
5 mM	0.2320 mL	1.1600 mL	2.3201 mL
10 mM	0.1160 mL	0.5800 mL	1.1600 mL

*Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (2.90 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (2.90 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (279 KB) SDS (418 KB)

COA (258 KB) HNMR (231 KB)

Handling Instructions (2659 KB)

References

[1]. Gustafsson A, et al. The association of erythromycin ethylsuccinate with acute colitis in horses in Sweden. Equine Vet J. 1997 Jul;29(4):314-8. [Content Brief]

[2]. Feng YC, et al. Construction of universal quantitative models for determination of roxithromycin and erythromycin ethylsuccinate in tablets from different manufacturers using near infrared reflectance spectroscopy. J Pharm Biomed Anal. 2006 May 3;41(2):373-84. [Content Brief]

[3]. Komuro I, et al. Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbeta. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12509-14. [Content Brief]

Erythromycin Ethylsuccinate Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords:

Erythromycin Ethylsuccinate1264-62-6Erythromycin ethyl EESBacterialHIVAutophagyAntibioticHuman immunodeficiency virusInhibitorinhibitorinhibit

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Erythromycin Ethylsuccinate (Synonyms: Erythromycin ethyl succinate; EES)

Other Forms of Erythromycin Ethylsuccinate:

Erythromycin Ethylsuccinate Related Antibodies

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