Direct red 254
Based on 1 Customer Validation
Direct Red 254 is a bisazo dye for textile applications. Direct Red 254 can be used for amyloid tissue staining in basic research on neurodegenerative diseases (e.g., Alzheimer's disease).
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- CAS No.: 6300-50-1
- 화학식: C22H15N5Na2O7S2
- 분자량:571.49
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보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
제품 설명
In Vitro
Direct Red 254 (1% (w/v)) stains amyloid-like synthetic peptides and induces birefringence in vitro: some peptide fragments with amyloid-like properties (e.g., peptide fragment N14) exhibit green birefringence under polarized light after staining. This is a typical characteristic of amyloid deposits[1].
Direct Red 254 can be effectively biodecolorized, and its decolorization efficiency is affected by its molecular structure and aggregation behavior in aqueous solution[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6300-50-1
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Appearance Solid
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분자량 571.49
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화학식 C22H15N5Na2O7S2
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Color black
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SMILES
O=S(C1=C(N=NC2=CC=C(N=NC3=CC=C(S(=O)(O[Na])=O)C=C3)C=C2)C(O)=C4C=CC(N)=CC4=C1)(O[Na])=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
순도&문서
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Data Sheet (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Hilbich C, et al. Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11. J Biol Chem. 1993;268(35):26571-26577. [Content Brief]
[2]. Brás R, et al. Monoazo and diazo dye decolourisation studies in a methanogenic UASB reactor. J Biotechnol. 2005;115(1):57-66. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)