Hepcidin-25 (human) TFA
Based on 1 Customer Validation
Hepcidin-25 (human) TFA is an iron metabolism modulator and Antimicrobial agent. Hepcidin-25 (human) TFA shows anti-inflammatory and anti-bacterial activity via modulation of iron-mediated oxidant injury.
For research use only. We do not sell to patients.
- Formula: C113H170N34O31S9.xC2HF3O2
- Molecular Weight:2789.35 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| Species | Dose | Route | T1/2 (Elimination) |
|---|---|---|---|
| Macaques | 11.1 nM | i.v. | 1.2 mg/mL |
Chemical Information
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Appearance Solid
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Molecular Weight 2789.35 (free base)
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Formula C113H170N34O31S9.xC2HF3O2
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SMILES
OC(C[C@H](N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CN=CN1)C(N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]4C(N[C@@](C(N[C@H](C(N[C@]5([H])C(N[C@@]6([H])CSSC[C@@]7([H])C(NCC(N[C@H](C(N[C@](CSSC[C@@](NC([C@](NC(CNC6=O)=O)([H])CSSC5)=O)([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N7)=O)CCCCN)=O)CO)=O)CCCNC(N)=N)=O)CC8=CN=CN8)=O)([H])C(N[C@@H](CSSC4)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)[C@H](O)C)=O)=O)=O)=O)CCSC)=O)=O)=O)=O)CC9=CC=CC=C9)=O)([H])[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F.[x]
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Sequence
Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr (Disulfide bridge:Cys7-Cys23; Cys10-Cys13; Cys11-Cys19; Cys14-Cys22)
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Sequence Shortening
DTHFPICIFCCGCCHRSKCGMCCKT (Disulfide bridge:Cys7-Cys23; Cys10-Cys13; Cys11-Cys19; Cys14-Cys22)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 25 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (286 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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