[BMIM]Cl
Based on 1 Customer Validation
[BMIM]Cl (1-butyl-3-methylimidazolium chloride) is an alkyl-imidazolium chloride compound and a persistent aquatic pollutant. [BMIM]Cl exhibits antimicrobial activity against S. aureus (MIC = 25 mM), E. coli (MIC = 50 mM), and P. aeruginosa (MIC = 100 mM). It possesses moderate membrane permeability and cytotoxicity, directly affecting microorganisms and mammalian cells at high concentrations, but can inhibit the function of complex ecosystems (e.g., anaerobic digestion) even at environmentally relevant low concentrations by disrupting microbial community structures. [BMIM]Cl can be used in research related to bacterial infections.
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 79917-90-1
- Formula: C8H15ClN2
- Molecular Weight:174.67
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | IC50 |
18.85 mM
Compound: [BMIM][Cl]
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Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay
Cytotoxicity against human Caco2 cells after 24 hrs by MTT assay
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[PMID: 26617961] |
[BMIM]Cl (0-200 mM; 18 hours) inhibits the growth of E. coli with an MIC of 50 mM, S. aureus with an MIC of 25 mM, and P. aeruginosa with an MIC of 100 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 79917-90-1
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Appearance Solid
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Molecular Weight 174.67
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Formula C8H15ClN2
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Color White to off-white
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SMILES
CN1C=C[N+](CCCC)=C1.[Cl-]
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Synonyms
1-Butyl-3-methylimidazolium chloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Purity & Documentation
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Data Sheet (266 KB)
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SDS (624 KB)
- English - EN (624 KB)
- Français - FR (624 KB)
- Deutsch - DE (624 KB)
- Norwegian - NO (624 KB)
- Español - ES (624 KB)
- Swedish - SV (624 KB)
- Italian - IT (624 KB)
- Korean - KR (624 KB)
- Portuguese - PT (624 KB)
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Handling Instructions (2659 KB)
References
[1]. Cook K, et al. Correlating Lipid Membrane Permeabilities of Imidazolium Ionic Liquids with their Cytotoxicities on Yeast, Bacterial, and Mammalian Cells. Biomolecules. 2019;9(6):251. Published 2019 Jun 25. [Content Brief]
[2]. Lu Q, et al. 1-Butyl-3-methylimidazolium Chloride Affects Anaerobic Digestion through Altering Organics Transformation, Cell Viability, and Microbial Community. Environ Sci Technol. 2023;57(8):3145-3155. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)