1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. D-Allothreonine

D-Allothreonine is the D type stereoisomer of Allothreonine. D-Allothreonine is a peptido-lipid derived from bacteria. D-Allothreonine, amide-linked to the D-galacturonic acid, is also a constituent in the polysaccharide.

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D-Allothreonine Chemical Structure

D-Allothreonine Chemical Structure

CAS No. : 24830-94-2

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500 mg USD 50 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of D-Allothreonine:

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  • Purity & Documentation

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Description

D-Allothreonine is the D type stereoisomer of Allothreonine. D-Allothreonine is a peptido-lipid derived from bacteria. D-Allothreonine, amide-linked to the D-galacturonic acid, is also a constituent in the polysaccharide[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

119.12

Formula

C4H9NO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N[C@H]([C@H](O)C)C(O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (209.87 mM; ultrasonic and warming and heat to 60°C)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.3949 mL 41.9745 mL 83.9490 mL
5 mM 1.6790 mL 8.3949 mL 16.7898 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 8.33 mg/mL (69.93 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.3949 mL 41.9745 mL 83.9490 mL 209.8724 mL
5 mM 1.6790 mL 8.3949 mL 16.7898 mL 41.9745 mL
10 mM 0.8395 mL 4.1974 mL 8.3949 mL 20.9872 mL
15 mM 0.5597 mL 2.7983 mL 5.5966 mL 13.9915 mL
20 mM 0.4197 mL 2.0987 mL 4.1974 mL 10.4936 mL
25 mM 0.3358 mL 1.6790 mL 3.3580 mL 8.3949 mL
30 mM 0.2798 mL 1.3991 mL 2.7983 mL 6.9957 mL
40 mM 0.2099 mL 1.0494 mL 2.0987 mL 5.2468 mL
50 mM 0.1679 mL 0.8395 mL 1.6790 mL 4.1974 mL
60 mM 0.1399 mL 0.6996 mL 1.3991 mL 3.4979 mL
80 mM 0.1049 mL 0.5247 mL 1.0494 mL 2.6234 mL
100 mM 0.0839 mL 0.4197 mL 0.8395 mL 2.0987 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-Allothreonine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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D-Allothreonine
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