Antibacterial agent 274
Antibacterial agent 274 (Compound 18b) is a membrane-targeting antibacterial agent that demonstrates a MIC of 8 μg/mL against Acinetobacter baumannii ATCC 17978. By disrupting bacterial membrane integrity, it induces intracellular ROS accumulation and causes leakage of DNA and proteins, thereby exhibiting potent antibacterial activity. This compound is suitable for research applications targeting Gram-negative bacterial infections.
For research use only. We do not sell to patients.
- Formula: C83H110BrCl2N11O23
- Molecular Weight:1780.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 1780.63
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Formula C83H110BrCl2N11O23
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SMILES
C[N+]1(CCCCCCCCCCCC)CCN(C([C@]([H])(C2=CC(O)=CC(O)=C23)NC([C@@]4([H])NC([C@]([H])(NC([C@@H](C5=CC(OC(C=C6)=C(Cl)C=C6[C@H]7O)=C(O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O[C@@H]9O[C@@H](C)[C@@H](O)[C@](N)(C)C9)C(OC(C=C%10)=C(Cl)C=C%10[C@H]4O)=C5)NC([C@H](CC(N)=O)NC([C@@H]7NC([C@@H](CC(C)C)NC)=O)=O)=O)=O)C%11=CC3=C(O)C=C%11)=O)=O)=O)CC1.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)