2. Anti-infection
  3. Bacterial Antibiotic
  4. Antibacterial agent 105

Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18，0.70，1.40，44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively.

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Antibacterial agent 105 Chemical Structure

Antibacterial agent 105 Chemical Structure

CAS No. : 2364493-24-1

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Antibacterial agent 105 Related Antibodies

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Description

Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18，0.70，1.40，44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively[1].

In Vitro

Antibacterial agent 105 (compound 17) has inhibitory effect on the growth of M. tuberculosis replicating in vitro cultured macrophages[1].
Antibacterial agent 105 (compound 17) (24 hours) has no toxicity on Vero cells line and human macrophages[1].
Antibacterial agent 105 (compound 17) has antibacterial activities against FQ resistant bacteria and XDR-TB[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 105 Related Antibodies
Molecular Weight

299.24

Formula

C14H9N3O5
CAS No.
SMILES

O=C(C1=CN(C)C2=C(C1=O)C=C([N+]([O-])=O)C3=CC=CN=C32)O
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Antibacterial agent 105 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 1052364493-24-1Antibacterial agent105Antibacterial agent-105BacterialAntibioticphenanthrolinic analogquinolonesantibacterial activityM. tuberculosisInhibitorinhibitorinhibit

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