Antibacterial agent 105
Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM). Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18, 0.70, 1.40, 44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2364493-24-1
- Formula: C14H9N3O5
- Molecular Weight:299.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Antibacterial agent 105 (compound 17) has inhibitory effect on the growth of M. tuberculosis replicating in vitro cultured macrophages[1].
Antibacterial agent 105 (compound 17) (24 hours) has no toxicity on Vero cells line and human macrophages[1].
Antibacterial agent 105 (compound 17) has antibacterial activities against FQ resistant bacteria and XDR-TB[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2364493-24-1
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Molecular Weight 299.24
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Formula C14H9N3O5
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SMILES
O=C(C1=CN(C)C2=C(C1=O)C=C([N+]([O-])=O)C3=CC=CN=C32)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 105 Related Classifications
HY-146098 Related Classifications
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