2364493-24-1
Chemical Structure
Antibacterial agent 105
- CAS No.: 2364493-24-1
- Formula:C14H9N3O5
- Molecular Weight:299.24
IUPAC Name: 1-methyl-6-nitro-4-oxo-1,4-dihydro-1,10-phenanthroline-3-carboxylic acid
InChIKey: RIEAJTBBEGOEKG-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C)C2=C(C1=O)C=C([N+]([O-])=O)C3=CC=CN=C32)O
Biological Activity: Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM). Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18, 0.70, 1.40, 44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively[1].
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Antibacterial agent 105 | Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM). Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18, 0.70, 1.40, 44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively. | |||||||||||||||||||||
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Keywords
