(-)-BO 2367
(-)-BO 2367, an antimicrobial quinolone, is a strong mammalian and bacterial topoisomerase II inhibitor. (-)-BO 2367 shows IC50 values with 3.8 μM, 0.5 μM, and 1 μM against the DNA relaxation activity of L1210 topoisomerase II and the supercoiling activities of Escherichia coli gyrase and Micrococcus luteus gyrase, respectively. (-)-BO 2367 is a potent antitumor agent.
For research use only. We do not sell to patients.
- CAS No.: 145902-81-4
- Formula: C21H22ClF2N3O3
- Molecular Weight:437.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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All Topoisomerase Isoforms
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Biological Activity
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Topoisomerase II |
Chemical Information
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CAS No. 145902-81-4
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Molecular Weight 437.87
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Formula C21H22ClF2N3O3
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SMILES
FC1=C2N(C3CC3)C=C(C(C2=CC(F)=C1N4C[C@@]5([H])[C@@](CC=C[C@H]5N)([H])C4)=O)C(O)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(-)-BO 2367 Related Classifications
HY-117657 Related Classifications
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