Galactinol dihydrate 

Galactinol dihydrate is a disaccharide carbohydrate serving as a galactosyl donor, which belongs to the raffinose family oligosaccharide pathway and acts as an important osmoprotectant. Galactinol dihydrate not only induces disease resistance in plants against fungal and bacterial pathogens, but also significantly enhances plant tolerance to abiotic stresses such as drought, high salinity, low temperature and oxidative damage. In addition, Galactinol dihydrate has the ability to scavenge hydroxyl radicals, can act as a signaling component for root colonization-induced systemic resistance, and is positively correlated with seed longevity in various crops, making it a potential biomarker for evaluating seed vigor. Therefore, Galactinol dihydrate can be used in the research of various plant diseases including fungal leaf spot, bacterial angular leaf spot, gray mold and soft rot^[1][2][3].

Galactinol dihydrate (0.5-10 mM) potently scavenges hydroxyl radicals in vitro with an ID₅₀ of 3.1 ± 0.3 mM and a second-order rate constant of 7.8 ± 0.81 × 10⁹ M^-1s^-1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Galactinol dihydrate (40.4-1,727 nmol/g fresh weight; endogenous production via transgene overexpression) in Arabidopsis thaliana ecotype Columbia plants confers protection against methylviologen-induced oxidative stress under control light intensity, as evidenced by preserved PSII activity, reduced lipid peroxidation, and maintained antioxidant pool levels^[1].
Galactinol dihydrate (40.4 ± 18.8-1,727 ± 366 nmol g^-1 fresh weight; endogenous production via transgene overexpression) in Arabidopsis thaliana ecotype Columbia plants confers protection against methylviologen-induced oxidative stress under high light intensity, as evidenced by reduced visible leaf injury, preserved PSII activity, and reduced lipid peroxidation^[1].
Galactinol dihydrate (40.4 ± 18.8-1,727 ± 366 nmol g^-1 fresh weight; endogenous production via transgene overexpression) in Arabidopsis thaliana ecotype Columbia plants confers protection against salinity stress, as evidenced by reduced visible leaf bleaching, preserved PSII activity, and reduced lipid peroxidation^[1].
Galactinol dihydrate (0.5-5 mM; root application) confers enhanced resistance to fungal and bacterial pathogens, tolerance to drought and high-salinity stress at 0.5 mM, while 5 mM induces expression of specific defense-related genes in wild-type tobacco^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

378.33

C₁₂H₂₆O₁₃

1217474-91-3

Solid

White to off-white

O[C@H]([C@H]([C@@H]([C@H]([C@H]1O)O)O)O)[C@@H]1O[C@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO.O.O

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Nishizawa A, et al. Galactinol and raffinose constitute a novel function to protect plants from oxidative damage. Plant Physiol. 2008 Jul;147(3):1251-63.  [Content Brief]

  [2]. Kim MS, et al. Galactinol is a signaling component of the induced systemic resistance caused by Pseudomonas chlororaphis O6 root colonization. Mol Plant Microbe Interact. 2008;21(12):1643-1653.  [Content Brief]

  [3]. de Souza Vidigal D, et al. Galactinol as marker for seed longevity. Plant Sci. 2016;246:112-118.  [Content Brief]