3,4-Dimethoxyphenol
Based on 1 Customer Validation
3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol exhibits broad-spectrum antimicrobial activity. 3,4-Dimethoxyphenol has tyrosinase-inhibiting activity. 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth. 3,4-Dimethoxyphenol can be used for the study of infection.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.97%
- CAS. Nr.: 2033-89-8
- Formel: C8H10O3
- Molecular Weight:154.16
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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HY-N1780R
3,4-Dimethoxyphenol (Standard)Anti-bacterical Agent -
HY-N0136
TaxifolinAntifibrotic Agent -
HY-N0192
ArbutinEndogenous Metabolite -
HY-N0136R
Taxifolin (Standard)Antifibrotic Agent -
HY-N1441
AfzelinFlavonol Glycoside -
HY-N0616
TrifolirhizinPterocarpan Flavonoid -
HY-107369
4-ButylresorcinolTyrosinase Inhibitor -
HY-N0192R
Arbutin (Standard)Endogenous Metabolite -
HY-W003607
3-O-Ethyl-L-ascorbic acidVitamin C Derivative -
HY-N4285
NegleteinFlavone -
HY-W038786
2,4,6-Trimethylphenol -
HY-N0445
2-Hydroxy-4-methoxybenzaldehydeTyrosinase Inhibitor
Biologische Aktivität
Beschreibung
In Vitro
3,4-Dimethoxyphenol (62.5-125 μg/mL) induces morphological damage in Xoo cells[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2033-89-8
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Appearance Solid
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Molecular Weight 154.16
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Formel C8H10O3
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Color Off-white to yellow
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SMILES
OC1=CC=C(OC)C(OC)=C1
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Structure Classification
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Initial Source
Aspergillus fumigatus
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (648.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (16.22 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (16.22 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Tanimoto S, et al. Synthesis and cosmetic whitening effect of glycosides derived from several phenylpropanoids. Yakugaku Zasshi. 2006 Mar;126(3):173-7. [Content Brief]
[3]. Lai J, et al. Transcriptome analysis reveals the inhibitory mechanism of 3,4-Dimethoxyphenol from Streptomyces albidoflavus strain ML27 against Xanthomonas oryzae pv. oryzae. Pestic Biochem Physiol. 2024 Jun;202:105913. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4868 mL | 32.4338 mL | 64.8677 mL | 162.1692 mL |
| 5 mM | 1.2974 mL | 6.4868 mL | 12.9735 mL | 32.4338 mL | |
| 10 mM | 0.6487 mL | 3.2434 mL | 6.4868 mL | 16.2169 mL | |
| 15 mM | 0.4325 mL | 2.1623 mL | 4.3245 mL | 10.8113 mL | |
| 20 mM | 0.3243 mL | 1.6217 mL | 3.2434 mL | 8.1085 mL | |
| 25 mM | 0.2595 mL | 1.2974 mL | 2.5947 mL | 6.4868 mL | |
| 30 mM | 0.2162 mL | 1.0811 mL | 2.1623 mL | 5.4056 mL | |
| 40 mM | 0.1622 mL | 0.8108 mL | 1.6217 mL | 4.0542 mL | |
| 50 mM | 0.1297 mL | 0.6487 mL | 1.2974 mL | 3.2434 mL | |
| 60 mM | 0.1081 mL | 0.5406 mL | 1.0811 mL | 2.7028 mL | |
| 80 mM | 0.0811 mL | 0.4054 mL | 0.8108 mL | 2.0271 mL | |
| 100 mM | 0.0649 mL | 0.3243 mL | 0.6487 mL | 1.6217 mL |
3,4-Dimethoxyphenol Related Classifications
HY-N1780 Related Classifications
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