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Monensin sodium

(Synonyms: Monensin A sodium)
43 Cited Publications
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Based on 43 publication(s) in Google Scholar

Monensin (Monensin A) sodium, an orally active antibiotic, is an ionophore that mediates Na+/H+ exchange. Monensin sodium is a potent Wnt signaling inhibitor. Monensin sodium causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin sodium can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects.

For research use only. We do not sell to patients.

  • Purity: 98.0%
  • CAS No.: 22373-78-0
  • Formula: C36H61NaO11
  • Molecular Weight:692.85
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Monensin sodium Chemical Structure
    Monensin sodium Chemical Structure
  • Experimental Validation Results for Monensin sodium
  • Experimental Validation Results for Monensin sodium
  • Experimental Validation Results for Monensin sodium
  • Experimental Validation Results for Monensin sodium
  • Experimental Validation Results for Monensin sodium
CAS No.: 22373-78-0
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Cell Migration/Invasion AssayCell Imaging/StainingWBRT-PCR
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  • Monensin sodium Chemical Structure
    Monensin sodium Chemical Structure
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    Monensin sodium purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2024 Dec 30;9(1):367. [Abstract]

    Customer Validation
     Cellular BiP-IRF2BP2 interactions shown by Western blot analysis of co-immunoprecipitation in MG132-pretreated (5 μM, 0.5 h) Raw264.7 cells which were treated with acidized medium (AcM) or with AcM plus Monensin (0.1 μM) in the presence of LPS and MG132 (0.5 μM) for 6 h.

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    Monensin sodium purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2024 Dec 30;9(1):367. [Abstract]

    Customer Validation
     Il1b expressions in BMDMs isolated from Hspa5f/f or Hspa5f/f; Lyz2-Cre mice treated with or without Monensin (1 μM), under stimulation of LPS for 24 h.

  • 1/16

    Monensin sodium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 18;16(1):6621. [Abstract]

    Customer Validation
     The impact of different concentrations of monensin on the subcellular localization of YFP-ATG8e. 5-day-old YFP-ATG8e transgenic seedlings were treated with different concentrations of Monensin (5-40 μM; 1 h) in 1/2MS liquid medium, followed by confocal microscopy observation.

  • 1/16

    Monensin sodium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 18;16(1):6621. [Abstract]

    Customer Validation
     Detection of ROS generation after monensin treatment. 5-day-old mCherry-ATG8f seedlings were subjected to Monensin (20 μM; 1 h) treatment. The ROS-sensitive dye H2DCFDA (1 μM) was incubated 10 min prior to confocal imaging. The images were shown with LUT pseudocolor scale.

  • 1/16

    Monensin sodium purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2025 Jul 15;122(28):e2501347122. [Abstract]

    Customer Validation
     Boyden chamber transwell assays on mesenchymal NSCLC cells treated with indicated doses of Monensin (100-500 nM; 24 h). Migrated and invaded cells were quantified.

  • Monensin sodium