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United States

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Cat. No.: HY-158375

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MBL-IN-4

MBL-IN-4 (compound 4b) is a MBL inhibitor with the IC₅₀ of 4.81 and 33 μM against IMP-1 and NDM-1.

For research use only. We do not sell to patients.

Formula: C₂₇H₃₆N₂O₂
Molecular Weight:420.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

MBL-IN-4 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MBL-IN-4 (compound 4b) is a MBL inhibitor with the IC₅₀ of 4.81 and 33 μM against IMP-1 and NDM-1^[1].

All Beta-lactamase Isoforms :

Chemical Information

Molecular Weight 420.59
Formula C₂₇H₃₆N₂O₂
SMILES

CC1=CC=C(C=C1)OCCCN(C2=CC=C3NC(CCC3=C2)=O)CCC4CCCCC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kamo T, et al. Development of Inhibitory Compounds for Metallo-beta-lactamase through Computational Design and Crystallographic Analysis. Biochemistry. 2024;63(10):1278-1286. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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