1. Anti-infection
  2. Antibiotic Bacterial
  3. Rhodomyrtone

Rhodomyrtone is an antibiotic that can be found in the leaves of Rhodomyrtus tomentosa. Rhodomyrtone kills Gram-positive bacterial cells without causing bacteriolysis. Rhodomyrtone exhibits activity against a variety of Gram-positive bacteria, including Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus salivarius. Rhodomyrtone is applicable to studies related to bacterial infections.

For research use only. We do not sell to patients.

Rhodomyrtone

Rhodomyrtone Chemical Structure

CAS No. : 468757-69-9

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Description

Rhodomyrtone is an antibiotic that can be found in the leaves of Rhodomyrtus tomentosa. Rhodomyrtone kills Gram-positive bacterial cells without causing bacteriolysis. Rhodomyrtone exhibits activity against a variety of Gram-positive bacteria, including Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus salivarius. Rhodomyrtone is applicable to studies related to bacterial infections[1][2].

Cellular Effect
Cell Line Type Value Description References
HEK293 IC50
11.4 μM
Compound: 5
Growth inhibition of HEK293 cells
Growth inhibition of HEK293 cells
[PMID: 28400231]
In Vitro

Rhodomyrtone exhibits significant antimicrobial activity against Escherichia coli and Staphylococcus aureus[1].
Rhodomyrtone (24 h) potently inhibits the growth of various Gram-positive bacterial strains, including MRSA, with MIC values ranging from 0.19 to 1.56 μg/mL[2].
Rhodomyrtone (24 h) exhibits concentration-dependent bactericidal activity against Streptococcus pyogenes; the bactericidal rate reaches ≥99.9% when treated at 2MBC for 24 h, 4MBC for 6 h, and 8MBC for 5 h[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

442.54

Formula

C26H34O6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)C[C@@H]1C2=C(O)C(C(CC(C)C)=O)=C(O)C=C2OC3=C1C(C(C)(C(C3(C)C)=O)C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: 95%

References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Rhodomyrtone
Cat. No.:
HY-N13668
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