Ceftolozane-15N2,d4 TFA
Ceftolozane-15N2,d4 (CXA-101-15N2,d4) TFA is the 15N- and deuterium-labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer.
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- Fòrmula: C25H27D4F3N1015N2O10S2
- Peso molecular:786.72
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Descripciòn
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 689293-68-3
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Peso molecular 786.72
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Fòrmula C25H27D4F3N1015N2O10S2
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SMILES
CN1[N+](CC(CS[C@]2([H])[C@@H]3NC(/C(C4=NSC(N)=N4)=N\OC(C)(C(O)=O)C)=O)=C(C([O-])=O)N2C3=O)=CC(NC([15NH]C([2H])([2H])C([2H])([2H])[15NH2])=O)=C1N.O=C(O)C(F)(F)F
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Synonyms
CXA-101-15N2,d4 TFA; FR264205-15N2,d4 TFA
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ceftolozane-15N2,d4 TFA Related Classifications
HY-19806S1 Related Classifications
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