2. Anti-infection
  3. Bacterial Fungal
  4. Tachyplesin-3

Tachyplesin-3 is a broad-spectrum cationic antimicrobial peptide. Tachyplesin-3 has inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, fungi and enveloped viruses. Tachyplesin-3 binds to bacterial membrane lipopolysaccharides through positive charges, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin-3 interferes with bacterial adhesion and aggregation, prevents biofilm formation, and has a synergistic effect when used in combination with Piperacillin (HY-B1923) - Tazobactam (HY-B1418) (TZP).

For research use only. We do not sell to patients.

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Tachyplesin-3

Tachyplesin-3 Chemical Structure

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Tachyplesin-3 Related Antibodies

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Description

Tachyplesin-3 is a broad-spectrum cationic antimicrobial peptide. Tachyplesin-3 has inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, fungi and enveloped viruses. Tachyplesin-3 binds to bacterial membrane lipopolysaccharides through positive charges, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin-3 interferes with bacterial adhesion and aggregation, prevents biofilm formation, and has a synergistic effect when used in combination with Piperacillin (HY-B1923) - Tazobactam (HY-B1418) (TZP)[1].

Molecular Weight

2236.71

Formula

C99H150N32O20S4
Sequence

Lys-Trp-Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Lys-Cys-Arg-NH2 (Disulfide bridge:Cys3-Cys16,Cys7-Cys12)
Sequence Shortening

KWCFRVCYRGICYRKCR-NH2 (Disulfide bridge:Cys3-Cys16,Cys7-Cys12)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tachyplesin-3 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tachyplesin-3Tachyplesin3Tachyplesin 3BacterialFungalAntimicrobial peptidePseudomonas aeruginosaBiofilm inhibitionUreteral stentPiperacillin-tazobactamSynergistic effectMedical device coatingRat subcutaneous modelBacterial adhesionInhibitorinhibitorinhibit

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