Antimicrobial agent-41
Antimicrobial agent-41 (Compound 19) is a thiazolidinedione derivative. Antimicrobial agent-41 exhibits excellent antioxidant activity (IC50 = 27.66 μg/mL). Antimicrobial agent-41 also exhibits antidiabetic activity (IC50 = 40.01 μg/mL). Antimicrobial agent-41 has antimicrobial activity again both bacterial and fungi.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 6325-95-7
- 分子式: C12H11NO4S
- 分子量:265.29
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
>100 μM
Compound: 18
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Antiproliferative activity against MCF7 cells after 72 hrs
Antiproliferative activity against MCF7 cells after 72 hrs
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[PMID: 17223347] |
| SK-BR-3 | IC50 |
>100 μM
Compound: 18
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Antiproliferative activity against SkBr3 cells after 72 hrs
Antiproliferative activity against SkBr3 cells after 72 hrs
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[PMID: 17223347] |
| SK-BR-3 | IC50 |
>100 μM
Compound: 18
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Induction of Hsp90-dependent Her2 protein degradation in Skbr3 cells after 24 hrs by ELISA
Induction of Hsp90-dependent Her2 protein degradation in Skbr3 cells after 24 hrs by ELISA
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[PMID: 17223347] |
化学情報
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CAS 番号 6325-95-7
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性状 Solid
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分子量 265.29
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分子式 C12H11NO4S
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Color White to off-white
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SMILES
O=C(NC/1=O)SC1=C\C2=CC=C(OC)C(OC)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
プロトコル
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antimicrobial agent-41 関連分類
HY-131051 関連分類
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