2. Cell Cycle/DNA Damage Anti-infection
  3. Topoisomerase Bacterial
  4. Topoisomerase IV inhibitor 2

Topoisomerase IV inhibitor 2 (compound 5d) is a potent DNA topoisomerase IV (TOPO IV) inhibitor with IC50s of 0.35 μM and 0.55 μM for TOPO IV and DNA gyrase, respectively. Topoisomerase IV inhibitor 2 has anti-bacterial activity, with MICs of 1.985 μM and 0.744 μM in Staphylococcus aureus Newman and Escherichia coli ATCC8739, respectively.

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Topoisomerase IV inhibitor 2

Topoisomerase IV inhibitor 2 화학구조

CAS No. : 2883403-36-7

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Topoisomerase IV inhibitor 2 Related Antibodies

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Topoisomerase Topo I Topo II DNA gyrase

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제품 설명

Topoisomerase IV inhibitor 2 (compound 5d) is a potent DNA topoisomerase IV (TOPO IV) inhibitor with IC50s of 0.35 μM and 0.55 μM for TOPO IV and DNA gyrase, respectively. Topoisomerase IV inhibitor 2 has anti-bacterial activity, with MICs of 1.985 μM and 0.744 μM in Staphylococcus aureus Newman and Escherichia coli ATCC8739, respectively[1].

IC50 & Target

TOPO IV

0.35 μM (IC50)

분자량

671.70

화학식

C33H30FN7O6S
CAS No.
SMILES

O=C(NC1=CC=C(C=C1)S(=O)(NC2=NC3=C(N=C2)C=CC=C3)=O)CN4CCN(CC4)C5=CC6=C(C(C(C(O)=O)=CN6C7CC7)=O)C=C5F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Topoisomerase IV inhibitor 2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase IV inhibitor 22883403-36-7Topoisomerase IV inhibitor2Topoisomerase IV inhibitor-2TopoisomeraseBacterialAntibacterialStaphylococcus aureusEscherichia coliDNA gyraseInhibitorinhibitorinhibit

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Topoisomerase IV inhibitor 2
Cat. No.:
HY-115991
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