LN-1-255 sodium
LN-1-255 sodium is a β-lactamase inhibitor. LN-1-255 sodium has broad-spectrum inhibitory effect on type D carbapenemases (CHDLs) with an IC50 for OXA-48 of 3 nM, and it also has strong activity against OXA-23, OXA-24/40, etc. LN-1-255 sodium combined with carbapenem antibiotics has a synergistic effect. LN-1-255 sodium can be used to study the bacterial resistance crisis caused by CHDLs.
For research use only. We do not sell to patients.
- CAS No.: 247115-03-3
- Formula: C22H19N2NaO9S
- Molecular Weight:510.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 247115-03-3
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Molecular Weight 510.45
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Formula C22H19N2NaO9S
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SMILES
O=C([C@@H]([C@](C)(COC(CC1=CC=C(O)C(O)=C1)=O)S([C@]2([H])/C3=C\C4=NC=CC=C4)(=O)=O)N2C3=O)O[Na]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Vallejo JA, et al. LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48. J Antimicrob Chemother. 2016 Aug;71(8):2171-80. [Content Brief]
[2]. Vázquez-Ucha JC, et al. Activity of the β-Lactamase Inhibitor LN-1-255 against Carbapenem-Hydrolyzing Class D β-Lactamases from Acinetobacter baumannii. Antimicrob Agents Chemother. 2017 Oct 24;61(11):e01172-17. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LN-1-255 sodium Related Classifications
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