SEC31B - SEC31 homolog B, COPII coat complex component Gene

Also Known as SEC31L2; SEC31B-1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 25956

About SEC31B

Cytogenetic location: 10q24.31 Genomic coordinates (GRCh38): 10:100,486,647-100,519,861 (from NCBI)

This gene has 13 transcripts (splice variants), 195 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 7.5), lymph node (RPKM 6.5) and 24 other tissues.

Summary

This gene encodes a protein of unknown function. The protein has moderate similarity to rat VAP1 protein which is an endosomal membrane-associated protein, containing a putative Ca2+/calmodulin-dependent kinase II phosphorylation site. [provided by RefSeq, Jul 2008]

SEC31B Products (1)

mRNA	Protein	Name
NM_015490.4	NP_056305.1	protein transport protein Sec31B

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Références	Source
part of vesicle coat	IDA IDA: Inferred from direct assay	22792322	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SEC31B Protein Structure

WD40

0
200
400
600
800
1000
1179 a.a.

Protein Preferred Names	Protein Names
protein transport protein Sec31B	SEC31 homolog B, COPII coating complex component

Related Diseases

Diseases	Alias
Retinitis Pigmentosa 47	RP47 Retinitis Pigmentosa, Type 47
Retinitis Pigmentosa 37	RP37 Retinitis Pigmentosa-37 Retinitis Pigmentosa, Type 37
Immunoglobulin A Deficiency 1	Immunoglobulin A Deficiency Selective Iga Deficiency Disease Selective Immunoglobulin A Deficiency IGAD1 Immunoglobulin A, Selective Deficiency Of Iga, Selective Deficiency Of Gamma-A-Globulin, Selective Deficiency Of Selective Iga Immunodeficiency Selective Iga Deficiency Iga Deficiency Selective
Hermansky-Pudlak Syndrome 1	Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells HPS1 Delta Storage Pool Disease Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Hermansky-Pudlak Syndrome, Type 1 Platelet Storage Pool Deficiency

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-RS12620	SEC31B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SEC31B	VGNC	VGNC:77293
Canis familiaris	SEC31B	VGNC	VGNC:45977
Rattus norvegicus	SEC31B	RGD	RGD:1598329
Mus musculus	SEC31B	MGD	MGI:2685187
Bos taurus	SEC31B	VGNC	VGNC:34418
Felis catus	SEC31B	VGNC	VGNC:64972
Others	SEC31B	NCBI