Atp5a1 - ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 Gene
Also Known as Atpm; Mom2; Atp5f1a; D18Ertd206e
Species: Mus musculus
Summary
Enables ATP binding activity and proton-transporting ATP Synthase activity, rotational mechanism. Acts upstream of or within lipid metabolic process. Located in membrane and mitochondrion. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 22 and mitochondrial complex V (ATP Synthase) deficiency nuclear type 4. Orthologous to human ATP5F1A (ATP Synthase F1 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]
Atp5a1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_007505.2 | NP_031531.1 | ATP synthase subunit alpha, mitochondrial precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables ATP binding |
IMP
IMP: Inferred from mutant phenotype
|
7916601 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
19941651 | MGI |
| enables proton-transporting ATP synthase activity, rotational mechanism |
IMP
IMP: Inferred from mutant phenotype
|
17612527 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within embryo development |
IMP
IMP: Inferred from mutant phenotype
|
17387143 | MGI |
| acts upstream of or within lipid metabolic process |
IMP
IMP: Inferred from mutant phenotype
|
17612527 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in membrane |
IMP
IMP: Inferred from mutant phenotype
|
20080761 | MGI |
| located in mitochondrion |
IDA
IDA: Inferred from direct assay
|
19808025 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ATP synthase subunit alpha, mitochondrial |
|