Fancb - Fanconi anemia, complementation group B Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 237211

Summary

Acts upstream of or within several processes, including cellular response to camptothecin; regulation of double-strand break repair via homologous recombination; and replication-born double-strand break repair via sister chromatid exchange. Predicted to be located in nucleus. Predicted to be part of Fanconi anaemia nuclear complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group B and head and neck squamous cell carcinoma. Orthologous to human FANCB (FA complementation group B). [provided by Alliance of Genome Resources, Apr 2022]

Fancb Products (2)

mRNA Protein Name
NM_001146081.2 NP_001139553.1 Fanconi anemia group B protein homolog isoform 1
NM_175027.5 NP_778192.3 Fanconi anemia group B protein homolog isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to camptothecin IGI
IGI: Inferred from genetic interaction
25520194 MGI
acts upstream of or within cellular response to xenobiotic stimulus IGI
IGI: Inferred from genetic interaction
25520194 MGI
acts upstream of or within cellular response to xenobiotic stimulus IMP
IMP: Inferred from mutant phenotype
25520194 MGI
acts upstream of or within negative regulation of double-strand break repair via homologous recombination IGI
IGI: Inferred from genetic interaction
25520194 MGI
acts upstream of or within positive regulation of double-strand break repair via homologous recombination IGI
IGI: Inferred from genetic interaction
25520194 MGI
acts upstream of or within replication-born double-strand break repair via sister chromatid exchange IMP
IMP: Inferred from mutant phenotype
25520194 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Fanconi anemia group B protein homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04733 FANCB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fancb NCBI NCBI:2187