Atp13a2 - ATPase cation transporting 13A2 Gene

Also Known as RGD1307977

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362645

Summary

Predicted to enable ABC-type polyamine transporter activity; phosphatidic acid binding activity; and phosphatidylinositol-3,5-bisphosphate binding activity. Involved in regulation of autophagosome size and regulation of mitochondrion organization. Predicted to be located in several cellular components, including cytoplasmic vesicle; neuronal cell body; and vacuole. Predicted to be integral component of lysosomal membrane. Human ortholog(s) of this gene implicated in Kufor-Rakeb syndrome; Parkinson's disease; and hereditary spastic paraplegia. Orthologous to human ATP13A2 (ATPase cation transporting 13A2). [provided by Alliance of Genome Resources, Apr 2022]

Atp13a2 Products (1)

mRNA Protein Name
NM_001173432.1 NP_001166903.1 polyamine-transporting ATPase 13A2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in regulation of autophagosome size IMP
IMP: Inferred from mutant phenotype
22186024 RGD
involved in regulation of mitochondrion organization IMP
IMP: Inferred from mutant phenotype
22186024 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polyamine-transporting ATPase 13A2

  • ATPase 13A2

  • ATPase type 13A2

  • probable cation-transporting ATPase 13A2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B2176S7 ATP-13C2 dilithium 96.0% Unkown
HY-RS01179 ATP13A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20208 Atp13a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26713 Atp13a2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp13a2 NCBI NCBI:23400