KCTD3 - potassium channel tetramerization domain containing 3 Gene

Also Known as NY-REN-45

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51133

About KCTD3

Cytogenetic location: 1q41 Genomic coordinates (GRCh38): 1:215,567,304-215,621,807 (from NCBI)

This gene has 5 transcripts (splice variants), 208 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 47.4), small intestine (RPKM 24.0) and 25 other tissues.

Summary

This gene encodes a member of the Potassium Channel tetramerization-domain containing (KCTD) protein family. Members of this protein family regulate the biophysical characteristics of ion channels. In mouse, this protein interacts with hyperpolarization-activated cyclic nucleotide-gated channel complex 3 and enhances its cell surface expression and current density. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

KCTD3 Products (3)

mRNA Protein Name
NM_001319294.2 NP_001306223.1 BTB/POZ domain-containing protein KCTD3 isoform 2
NM_001319295.2 NP_001306224.1 BTB/POZ domain-containing protein KCTD3 isoform 3
NM_016121.5 NP_057205.2 BTB/POZ domain-containing protein KCTD3 isoform 1

KCTD3 Protein Structure

BTB_2

BTB_2: BTB/POZ domain (20 - 105)

  • 0
  • 200
  • 400
  • 600
  • 815 a.a.
Protein Preferred Names Protein Names

BTB/POZ domain-containing protein KCTD3

  • NY-REN-45 antigen

KCTD3 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83392 KCTD3 Antibody (YA3137) WB Human
HY-P83392A KCTD3 Antibody (YA3137)(PBS only) WB Human
HY-P86269 KCTD3 Antibody (YA5961) WB Human

Related Diseases

Diseases Alias
Scalp-Ear-Nipple Syndrome

  • Finlay-Marks Syndrome

  • Sen Syndrome

  • SENS

  • Scalp Ear Nipple Syndrome

  • Hereditary Syndrome Of Lumpy Scalp, Odd Ears And Rudimentary Nipples

  • Hereditary Syndrome Of Lumpy Scalp, Odd Ears, And Rudimentary Nipples

  • Indian Childhood Cirrhosis
Variegate Porphyria

  • Porphyria Variegata

  • Protoporphyrinogen Oxidase Deficiency

  • VP

  • Ppox Deficiency

  • Porphyria, South African Type

  • Porphyria Variegata, Susceptibility To

  • Protocoproporphyria

  • Porphyria Variegate

  • Porphyria South African Type

  • Pv

  • Porphyria, Variegate

  • Vp - [Variegate Porphyria]
West Syndrome

  • Infantile Spasms

  • Infantile Spasms Syndrome

  • Infantile Spasm

  • X-Linked Infantile Spasm Syndrome

  • X-Linked Infantile Spasms

  • Epileptic Encephalopathy, Early Infantile, 1

  • Is

  • Tonic Spasms With Clustering, Arrest Of Psychomotor Development And Hypsarrhythmia On Eeg

  • West'S Syndrome

  • Spasms, Infantile

  • Is -[Infantile Spasm]

  • Salaam Spasm

  • Salaam Tic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07195 KCTD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus KCTD3 MGD MGI:2444629
Macaca mulatta KCTD3 VGNC VGNC:73875
Bos taurus KCTD3 VGNC VGNC:97280
Felis catus KCTD3 VGNC VGNC:63062
Canis familiaris KCTD3 VGNC VGNC:42307
Rattus norvegicus KCTD3 RGD RGD:1310658
Others KCTD3 NCBI