RAB30 - RAB30, member RAS oncogene family Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 27314

About RAB30

Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:82,973,133-83,071,897 (from NCBI)

This gene has 16 transcripts (splice variants), 203 orthologues and 68 paralogues. Ubiquitous expression in brain (RPKM 7.4), lymph node (RPKM 5.8) and 24 other tissues.

Summary

Predicted to enable GTP binding activity and GTPase activity. Involved in Golgi organization. Located in Golgi cisterna; cis-Golgi network; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]

RAB30 Products (4)

mRNA Protein Name
NM_001286059.2 NP_001272988.1 ras-related protein Rab-30
NM_001286060.2 NP_001272989.1 ras-related protein Rab-30
NM_001286061.1 NP_001272990.1 ras-related protein Rab-30
NM_014488.5 NP_055303.2 ras-related protein Rab-30

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in Golgi organization IMP
IMP: Inferred from mutant phenotype
22188167 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in Golgi cisterna IDA
IDA: Inferred from direct assay
22188167 GOA
located in cis-Golgi network IDA
IDA: Inferred from direct assay
22188167 GOA
located in trans-Golgi network IDA
IDA: Inferred from direct assay
22188167 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB30 Protein Structure

Ras

Ras: Ras family (11 - 168)

  • 0
  • 100
  • 203 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-30

RAB30 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
RAB30 Q15771 AGTRAP Homo sapiens Q6RW13-2
Y2H Array
32296183
Intra
RAB30 Q15771 AGTRAP Homo sapiens Q6RW13-2
Y2H Prey Pooling
32296183
Intra
RAB30 Q15771 AGTRAP Homo sapiens Q6RW13-2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Syndromic X-Linked Intellectual Disability Shashi Type

  • Mental Retardation, X-Linked, Syndromic 11, Shashi Type

  • Mrxs11

  • Shashi X-Linked Mental Retardation Syndrome

  • Smrxs

  • Syndromic X-Linked Intellectual Disability Type 11

  • X-Linked Mental Retardation Shashi Type

  • Mental Retardation, X-Linked, Syndromic 11
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11543 RAB30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus RAB30 RGD RGD:1309507
Mus musculus RAB30 MGD MGI:1923235
Canis familiaris RAB30 VGNC VGNC:45273
Felis catus RAB30 VGNC VGNC:81955
Bos taurus RAB30 VGNC VGNC:33639
Macaca mulatta RAB30 VGNC VGNC:81531
Others RAB30 NCBI