2007-00-3
2007-00-3
Chemical Structure
Iodoquine
- CAS. Nr.: 2007-00-3
- Formula:C18H26IN3
- Molecular Weight:411.32
InChIKey: QCZZTGLRWDAZMG-UHFFFAOYSA-N
SMILES: IC1=CC2=NC=CC(NC(CCCN(CC)CC)C)=C2C=C1
Biological Activity: Iodoquine is an analog of chloroquine. Iodoquine exhibits high uptake in tumor cells and can localize to cells with high ALDH1 content, including cancer stem cells. With low uptake in normal brain tissue, iodoquine can be used in research related to tumor diagnosis or as a radiotracer[1][2].
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Iodoquine | Iodoquine is an analog of chloroquine. Iodoquine exhibits high uptake in tumor cells and can localize to cells with high ALDH1 content, including cancer stem cells. With low uptake in normal brain tissue, iodoquine can be used in research related to tumor diagnosis or as a radiotracer. | |||||||||||||||||||||
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References
- [1]. Chin BB, et al. Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression. Curr Radiopharm. 2012 Jan;5(1):47-58. [Content Brief]
- [2]. Chin B, et al. Iodoquine as a potential PET radiolabel for in vivo cell trafficking of leukocyte tumor cell lines. 2012.
Keywords
