2342576-75-2

ASM-IN-3 Chemical Structure
2342576-75-2

Chemical Structure

ASM-IN-3

  • CAS. Nr.: 2342576-75-2
  • Formula:C17H13ClN2O4
  • Molecular Weight:344.75

SMILES: O=C(C1=CC(OCC2=CC=C(C3=CC=C(Cl)C=C3)C=C2)=NO1)NO

Biological Activity: ASM-IN-3 (Compound 21b) is a selective and BBB-penetrating acid sphingomyelinase (ASM) inhibitor (IC50: 3.37 μM for pure human ASM). ASM-IN-3 improves depression-like behaviors by inhibiting ASM activity and increasing neurogenesis in hippocampus in Reserpine (HY-N0480)-induced depressed rats[1].

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-171033 		ASM-IN-3 ASM-IN-3 (Compound 21b) is a selective and BBB-penetrating acid sphingomyelinase (ASM) inhibitor (IC50: 3.37 μM for pure human ASM). ASM-IN-3 improves depression-like behaviors by inhibiting ASM activity and increasing neurogenesis in hippocampus in Reserpine (HY-N0480)-induced depressed rats.
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