3027529-88-7
3027529-88-7
Chemical Structure
HZS60
- CAS. Nr.: 3027529-88-7
- Formula:C13H17F2N3
- Molecular Weight:253.29
SMILES: FC1=CC=C(C#N)C(F)=C1C(C)N(CC)CCN
Biological Activity: HZS60 is a NMDAR/TRPM4 inhibitor with brain permeability that can improve cerebral ischemia. HZS60 has significant neuroprotective effects on primary neuronal ischemic damage caused by NMDA and oxygen-glucose deprivation/reoxygenation. HZS60 exhibits good pharmacokinetic characteristics and can inhibit cerebral ischemia-reperfusion injury. HZS60 can be used as a potential inhibitor of ischemic stroke[1].
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HZS60 | HZS60 is a NMDAR/TRPM4 inhibitor with brain permeability that can improve cerebral ischemia. HZS60 has significant neuroprotective effects on primary neuronal ischemic damage caused by NMDA and oxygen-glucose deprivation/reoxygenation. HZS60 exhibits good pharmacokinetic characteristics and can inhibit cerebral ischemia-reperfusion injury. HZS60 can be used as a potential inhibitor of ischemic stroke. | |||||||||||||||||||||
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References
Keywords
