Hsd3b7 - hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 101502

Summary

Enables cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity. Involved in B cell chemotaxis. Predicted to be located in intracellular membrane-bounded organelle and lipid droplet. Is expressed in several structures, including alimentary system; bladder; facial bone primordium; heart; and liver and biliary system. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 1 and intrahepatic cholestasis. Orthologous to human HSD3B7 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7). [provided by Alliance of Genome Resources, Apr 2022]

Hsd3b7 Products (2)

mRNA Protein Name
NM_001040684.2 NP_001035774.1 3 beta-hydroxysteroid dehydrogenase type 7 isoform b
NM_133943.3 NP_598704.2 3 beta-hydroxysteroid dehydrogenase type 7 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity IMP
IMP: Inferred from mutant phenotype
22999953 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in B cell chemotaxis IMP
IMP: Inferred from mutant phenotype
22999953 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3 beta-hydroxysteroid dehydrogenase type 7

  • 3 beta-hydroxysteroid dehydrogenase type VII

  • 3-beta-HSD VII

  • 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase

  • c(27) 3-beta-HSD

  • cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS06403 HSD3B7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd3b7 NCBI NCBI:80270