Amacr - alpha-methylacyl-CoA racemase Gene

Also Known as Da1-8; Marc1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25284

Summary

Enables alpha-methylacyl-CoA racemase activity. Involved in bile acid biosynthetic process. Located in mitochondrion and peroxisome. Human ortholog(s) of this gene implicated in alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary bladder Cancer. Orthologous to human AMACR (alpha-methylacyl-CoA racemase). [provided by Alliance of Genome Resources, Apr 2022]

Amacr Products (1)

mRNA Protein Name
NM_012816.2 NP_036948.2 alpha-methylacyl-CoA racemase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables alpha-methylacyl-CoA racemase activity IDA
IDA: Inferred from direct assay
8020470 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in bile acid biosynthetic process IDA
IDA: Inferred from direct assay
11964182 RGD
involved in bile acid metabolic process IDA
IDA: Inferred from direct assay
8020470 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in mitochondrion IDA
IDA: Inferred from direct assay
7649182 RGD
located in peroxisome IDA
IDA: Inferred from direct assay
11060359 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-methylacyl-CoA racemase

  • 2-arylpropionyl-CoA epimerase

  • 2-methylacyl-CoA racemase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS00640 AMACR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19981 Amacr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26485 Amacr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amacr NCBI NCBI:23600