AK5 - adenylate kinase 5 Gene

Also Known as AK6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 26289

About AK5

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:77,282,019-77,559,966 (from NCBI)

This gene has 13 transcripts (splice variants), 208 orthologues and 9 paralogues. Biased expression in brain (RPKM 40.3) and testis (RPKM 0.8).

Summary

This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

AK5 Products (2)

mRNA Protein Name
NM_012093.4 NP_036225.2 adenylate kinase isoenzyme 5 isoform 2
NM_174858.3 NP_777283.1 adenylate kinase isoenzyme 5 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables nucleoside diphosphate kinase activity IDA
IDA: Inferred from direct assay
23416111 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AK5 Protein Structure

ADK

ADK: Adenylate kinase (137 - 293)

ADK

ADK: Adenylate kinase (381 - 536)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 562 a.a.
Protein Preferred Names Protein Names

adenylate kinase isoenzyme 5

  • AK 5

Related Diseases

Diseases Alias
Limbic Encephalitis
Anterograde Amnesia

  • Amnesia, Anterograde
Chronic Frontal Sinusitis
Dissociative Amnesia

  • Psychogenic Amnesia

  • Amnesia, Dissociative

  • Amnesia, Psychogenic

  • Amnesia Neurosis

  • Hysterical Fugue

  • Dissociative Fugue
Transient Global Amnesia

  • Amnesia, Transient Global
Reticular Dysgenesis

  • Severe Combined Immunodeficiency With Leukopenia

  • De Vaal Disease

  • Congenital Aleukia

  • Aleukocytosis

  • Hematopoietic Hypoplasia, Generalized

  • Reticular Dysgenesia

  • Devaal Disease

  • Rd

  • Ak2 Deficiency

  • Congenital Aleukocytosis

  • Generalized Hematopoietic Hypoplasia

  • Scid With Leukopenia

  • RDYS
Connective Tissue Benign Neoplasm

  • Soft Tissue Neoplasms

  • Mesenchymal Tissue Neoplasm

  • Neoplasm Of Soft Tissue

  • Neoplasm Of Soft Tissues

  • Soft Tissue Benign Neoplasm

  • Tumor Of The Soft Tissue

  • Soft Tissue Neoplasm
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS00508 AK5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19858 Ak5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26358 Ak5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris AK5 VGNC VGNC:37747
Rattus norvegicus AK5 RGD RGD:1590818
Macaca mulatta AK5 VGNC VGNC:69762
Bos taurus AK5 VGNC VGNC:25774
Felis catus AK5 VGNC VGNC:59707
Mus musculus AK5 MGD MGI:2677491
Others AK5 NCBI