Erlin2 - ER lipid raft associated 2 Gene

Also Known as Spfh2; RGD1309010

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 290823

Summary

Predicted to enable Cholesterol binding activity and ubiquitin protein Ligase binding activity. Predicted to be involved in SREBP signaling pathway; negative regulation of lipid biosynthetic process; and ubiquitin-dependent ERAD pathway. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum; and membrane raft. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 18. Orthologous to human ERLIN2 (ER lipid raft associated 2). [provided by Alliance of Genome Resources, Apr 2022]

Erlin2 Products (1)

mRNA Protein Name
NM_001106088.2 NP_001099558.1 erlin-2
Protein Preferred Names Protein Names

erlin-2

  • SPFH domain family, member 2

  • SPFH domain-containing protein 2

  • endoplasmic reticulum lipid raft-associated protein 2

  • stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS04502 ERLIN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Erlin2 NCBI NCBI:11160