Urod - uroporphyrinogen decarboxylase Gene

Also Known as porphyrinogen carboxy-lyase

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29421

Summary

Enables ferrous iron binding activity and uroporphyrinogen decarboxylase activity. Involved in several processes, including porphyrin-containing compound metabolic process; response to estradiol; and response to fungicide. Located in cytosol. Biomarker of porphyria and porphyria cutanea tarda. Human ortholog(s) of this gene implicated in porphyria cutanea tarda. Orthologous to human UROD (uroporphyrinogen decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

Urod Products (1)

mRNA Protein Name
NM_019209.1 NP_062082.1 uroporphyrinogen decarboxylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables ferrous iron binding IDA
IDA: Inferred from direct assay
515872 RGD
enables uroporphyrinogen decarboxylase activity IDA
IDA: Inferred from direct assay
15736160 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in cellular response to arsenic-containing substance IEP
IEP: Inferred from expression pattern
10416273 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
6219675 RGD
involved in porphyrin-containing compound biosynthetic process IDA
IDA: Inferred from direct assay
12381387 RGD
involved in response to amine IEP
IEP: Inferred from expression pattern
10365252 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
3945969 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
12426626 RGD
involved in response to fungicide IEP
IEP: Inferred from expression pattern
19482825 RGD
involved in response to iron ion IEP
IEP: Inferred from expression pattern
891100 RGD
involved in response to mercury ion IEP
IEP: Inferred from expression pattern
6482878 RGD
involved in response to methylmercury IEP
IEP: Inferred from expression pattern
3327437 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
4023421 RGD
involved in uroporphyrinogen III metabolic process IDA
IDA: Inferred from direct assay
15736160 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uroporphyrinogen decarboxylase

  • UPD

  • URO-D

  • porphyrinogen carboxylase

  • uroporphyrinogen III decarboxylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15509 UROD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21453 Urod Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27971 Urod Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Urod NCBI NCBI:7389