Trmu - tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase Gene

Also Known as Trmt1; 1110005N20Rik; 1600025P05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72026

Summary

Predicted to enable ATP binding activity; sulfurtransferase activity; and tRNA binding activity. Predicted to be involved in tRNA wobble position uridine thiolation. Located in mitochondrion. Used to study liver disease. Human ortholog(s) of this gene implicated in aminoglycoside-induced deafness; infantile liver failure syndrome; and transient infantile liver failure. Orthologous to human TRMU (tRNA mitochondrial 2-thiouridylase). [provided by Alliance of Genome Resources, Apr 2022]

Trmu Products (1)

mRNA Protein Name
NM_028063.2 NP_082339.1 mitochondrial tRNA-specific 2-thiouridylase 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
14746906 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial tRNA-specific 2-thiouridylase 1

  • tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15097 TRMU Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trmu NCBI NCBI:55687