74578-01-1
Chemical Structure
Thaspine acetate
- CAS No.: 74578-01-1
- Formula:C22H23NO8
- Molecular Weight:429.42
IUPAC Name: 1-(2-(dimethylamino)ethyl)-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione acetate
InChIKey: HUNGYFRUEMVMMI-UHFFFAOYSA-N
SMILES: O=C1C2=CC=C(OC)C(O3)=C2C4=C(C3=O)C(CCN(C)C)=CC(OC)=C4O1.CC(O)=O
Biological Activity: Thaspine acetate, an alkaloid, is a topoisomerase I and II inhibitor. Thaspine acetate induces cancer cell apoptosis. Thaspine acetate induces Bak and Bax activation, mitochondrial cytochrome c release and mitochondrial membrane permeabilization. Thaspine acetate can be isoalted from the cortex of the South American tree Croton lechleri[1].
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Thaspine acetate | Thaspine acetate, an alkaloid, is a topoisomerase I and II inhibitor. Thaspine acetate induces cancer cell apoptosis. Thaspine acetate induces Bak and Bax activation, mitochondrial cytochrome c release and mitochondrial membrane permeabilization. Thaspine acetate can be isoalted from the cortex of the South American tree Croton lechleri. | |||||||||||||||||||||
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Keywords
