905853-99-8
Chemical Structure
(rel)-Tivantinib
Synonym(s): (rel)-ARQ 197; (rel)-(3R,4R)-ARQ 198
- CAS No.: 905853-99-8
- Formula:C23H19N3O2
- Molecular Weight:369.42
IUPAC Name: (3R,4R)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione
InChIKey: UCEQXRCJXIVODC-PMACEKPBSA-N
SMILES: O=C(NC1=O)[C@@H](C2=CN3C4=C(C=CC=C42)CCC3)[C@@H]1C5=CNC6=C5C=CC=C6
Biological Activity: (rel)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (rel)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(rel)-Tivantinib | 96.45% | (rel)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (rel)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC). | ||||||||||||||||||||
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Keywords
