Atp2a3 - ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 Gene

Also Known as SERCA3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25391

Summary

Enables P-type calcium transporter activity and calcium-dependent ATPase activity. Involved in calcium ion transmembrane transport; endoplasmic reticulum calcium ion homeostasis; and liver regeneration. Predicted to be located in organelle membrane and sarcoplasmic reticulum. Predicted to be integral component of membrane. Biomarker of hypertension. Orthologous to human ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3). [provided by Alliance of Genome Resources, Apr 2022]

Atp2a3 Products (1)

mRNA Protein Name
NM_012914.1 NP_037046.1 sarcoplasmic/endoplasmic reticulum calcium ATPase 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables P-type calcium transporter activity IDA
IDA: Inferred from direct assay
9843705 RGD
enables calcium ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
11956212 RGD
enables calcium-dependent ATPase activity IDA
IDA: Inferred from direct assay
9843705 RGD
Biological Process GO Annotation Evidence References Source
involved in calcium ion transmembrane transport IDA
IDA: Inferred from direct assay
9843705 RGD
involved in endoplasmic reticulum calcium ion homeostasis IDA
IDA: Inferred from direct assay
11956212 RGD
involved in liver regeneration IEP
IEP: Inferred from expression pattern
11032760 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sarcoplasmic/endoplasmic reticulum calcium ATPase 3

  • ATPase, Ca++ transporting, ubiquitous

  • SR Ca(2+)-ATPase 3

  • calcium pump 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01193 ATP2A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01196 ATP2B3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp2a3 NCBI NCBI:489