Ikbkg - inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Gene

Also Known as Nemo

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 309295

Summary

Enables peroxisome proliferator activated receptor binding activity. Predicted to be involved in several processes, including anoikis; regulation of gene expression; and regulation of signal transduction. Predicted to act upstream of or within B cell homeostasis and activation of NF-kappaB-inducing kinase activity. Located in cytosol. Part of IkappaB kinase complex. Used to study irritable bowel syndrome and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in Behcet's disease; Bloch-Sulzberger syndrome; immunodeficiency 33; and learning disability. Orthologous to human IKBKG (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ikbkg Products (1)

mRNA Protein Name
NM_199103.2 NP_954534.1 NF-kappa-B essential modulator

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables peroxisome proliferator activated receptor binding IPI
IPI: Inferred from physical interaction
18828195 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
17419723 RGD
Cellular Component GO Annotation Evidence References Source
part of IkappaB kinase complex IDA
IDA: Inferred from direct assay
17419723 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NF-kappa-B essential modulator

  • I-kappa-B kinase gamma

  • I-kappa-B kinase subunit gamma

  • IKK-gamma

  • IKKAP1

  • IKKG

  • NF-kappa-B essential modifier

  • ikB kinase subunit gamma

  • ikB kinase-associated protein 1

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

  • inhibit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06664 IKBKG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ikbkg NCBI NCBI:8517