Zmpste24 - zinc metallopeptidase STE24 Gene

Predicted to enable double-stranded DNA binding activity and metalloendopeptidase activity. Predicted to be involved in CAAX-box protein processing. Predicted to act upstream of or within several processes, including animal organ development; regulation of intracellular signal transduction; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in membrane and nuclear envelope. Predicted to be part of protein-containing complex. Predicted to be integral component of endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in connective tissue disease and lethal restrictive dermopathy. Orthologous to human ZMPSTE24 (zinc metallopeptidase STE24). [provided by Alliance of Genome Resources, Apr 2022]