Sptlc2 - serine palmitoyltransferase, long chain base subunit 2 Gene

Also Known as LCB 2; Pomt2; SPT 2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 366697

Summary

Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in adipose tissue development; ceramide biosynthetic process; and sphingosine biosynthetic process. Predicted to act upstream of or within positive regulation of lipophagy; sphinganine biosynthetic process; and sphingomyelin biosynthetic process. Predicted to be integral component of membrane. Predicted to be part of serine C-palmitoyltransferase complex. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Orthologous to human SPTLC2 (serine palmitoyltransferase long chain base subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Sptlc2 Products (1)

mRNA Protein Name
NM_001037097.2 NP_001032174.1 serine palmitoyltransferase 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
34449011 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine palmitoyltransferase 2

  • long chain base biosynthesis protein 2

  • protein-O-mannosyltransferase 2

  • serine-palmitoyl-CoA transferase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13737 SPTLC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sptlc2 NCBI NCBI:9517