1852495-86-3
1852495-86-3
Chemical Structure
(Rac)-MGV354
- CAS No.: 1852495-86-3
- Formula:C35H37N5O3
- Molecular Weight:575.70
IUPAC Name: 1-(6-(3-((4-(1-(cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid
InChIKey: MAUQVVDVXCBOHQ-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)N(C2=NC(C3=CC=CC4=C3C(NC5=CC=C(C6CCN(C(C7CC7)=O)CC6)C=C5C)CC4)=CC=C2)N=C1)O
Biological Activity: (Rac)-MGV354 is the racemate of MGV354. MGV354 is a soluble guanylate cyclase (sGC) activator with EC50s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively[1].
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(Rac)-MGV354 | 99.56% | (Rac)-MGV354 is the racemate of MGV354. MGV354 is a soluble guanylate cyclase (sGC) activator with EC50s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively. | ||||||||||||||||||||
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References
Keywords
