2760881-74-9
2760881-74-9
Chemical Structure
BRD0639
- CAS No.: 2760881-74-9
- Formula:C21H22ClN5O4S
- Molecular Weight:475.95
IUPAC Name: (S)-2-(4-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-(N-(2-(pyridin-2-yl)ethyl)sulfamoyl)phenyl)propanamide
InChIKey: BXDCFRRDENJUJM-HNNXBMFYSA-N
SMILES: C[C@H](N1C(C=C(Cl)C=N1)=O)C(NC2=CC=C(C)C(S(=O)(NCCC3=NC=CC=C3)=O)=C2)=O
Biological Activity: BRD0639 is a first-in-class inhibitor of the PRMT5-substrate adaptor interaction. BRD0639 is a PRMT5 binding motif (PBM)-competitive agent that can support studies of PBM dependent PRMT5 activities[1].
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BRD0639 | 98.04% | BRD0639 is a first-in-class inhibitor of the PRMT5-substrate adaptor interaction. BRD0639 is a PRMT5 binding motif (PBM)-competitive agent that can support studies of PBM dependent PRMT5 activities. | ||||||||||||||||||||
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References
Keywords
